The clinical significance of variations in ethanol toxicokinetics

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effects of ethanol on the toxicokinetics of methamphetamine in rabbits

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In the current study, the effects of ethanol (EtOH) on toxicokinetics of methamphetamine (MA) and its metabolite amphetamine (AP) were investigated. A single dose of MA hydrochloride at 15 mg/Kg was given intragastrically, either alone (MA group; n = 8) or in conjunction with 3 g/Kg EtOH (MA+EtOH group; n = 8) to rabbits. In placebo group, normal saline only was given (placebo group; n = 4). Pl...

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ژورنال

عنوان ژورنال: Journal of Medical Toxicology

سال: 2007

ISSN: 1556-9039,1937-6995

DOI: 10.1007/bf03160911